Zepbound® (GLP-1/GIP) injections online

Tirzepatide is a dual GIP and GLP-1 receptor agonist, which means it acts like two natural gut hormones—GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1)—that help regulate blood sugar, appetite, and digestion.

By activating both pathways, tirzepatide can:
• Increase insulin release when blood sugar is elevated
• Reduce glucagon, the hormone that tells your liver to release stored sugar
• Slow how quickly the stomach empties, helping you feel fuller for longer after meals
• Lower appetite and cravings, which can naturally reduce how much you eat

Together, these effects can support better blood sugar control and medically supervised weight loss when tirzepatide is used as part of a structured treatment plan with clinical monitoring, nutrition, and lifestyle changes.

Zepbound® (tirzepatide) is an FDA-approved GLP-1/GIP injection used for chronic weight management in adults living with obesity, or in overweight adults who also have weight-related health conditions such as high blood pressure, type 2 diabetes, sleep apnea, cardiovascular disease, or high cholesterol. It is always used together with changes in nutrition, activity, and lifestyle—not as a stand-alone quick fix.

Tirzepatide belongs to a class of medicines called GIP and GLP-1 receptor agonists. By activating both receptors, Zepbound® can:
• increase insulin release when blood sugar levels are high
• reduce glucagon, the hormone that signals the liver to release stored sugar
• slow how quickly food leaves the stomach, helping you feel fuller for longer
• decrease appetite and cravings, which can support reduced calorie intake and weight loss over time

At Fittlly, Zepbound® is prescribed only after a licensed clinician reviews your health history and determines that it is a safe and appropriate option within a structured medical weight management plan.

Zepbound® (tirzepatide) is taken as a subcutaneous (under the skin) injection once a week, after you’ve been shown how to use it by your care team. Common injection sites include:
• the abdomen, at least 2 inches away from the belly button
• the front or outer part of the thigh
• the outer back of the upper arm (this area should be injected by someone else)

Key points to remember:
• Rotate injection sites with each dose, and avoid scars, moles, irritated skin, or bruises. Never inject through clothing.
• Check the medication before use: the liquid in the pen should be clear and colorless. Do not use it if it looks cloudy, discolored, or contains particles.
• Always use a new, sterile needle for each injection, and never share pens, needles, or syringes with anyone else. Sharing devices can transmit infections.
• Use Zepbound® on the same day each week, at any time of day, with or without food, unless your clinician gives you different instructions.
• Follow the step-by-step instructions provided with your Zepbound® pen and any training from your clinician or pharmacist. If you’re unsure about your injection technique or have questions, contact your healthcare provider before using the medication.

Weight loss with Zepbound® (tirzepatide) varies from person to person, and no one can guarantee a specific amount of weight you will lose. Your starting weight, health conditions, dose, lifestyle, and consistency all influence your results.

In a 72-week clinical trial of Zepbound® 15 mg in adults without diabetes but with obesity or excess weight plus a weight-related condition, patients lost on average about 20% of their body weight when Zepbound® was combined with diet and exercise changes. In the same study, people who only received diet and exercise support lost about 3.1% of their body weight.

Your own results may be higher or lower than these averages. At Fittlly, Zepbound® is always used as part of a supervised medical weight management plan, with a focus on safe, sustainable progress over time, not extreme or rapid weight loss at any cost.

The timeline for seeing results with Zepbound® (tirzepatide) is different for everyone. Some people notice changes in appetite or portion sizes within the first few weeks, while for others visible weight loss may take a month or more. Both patterns can be normal, especially while your dose is being slowly increased.

What matters most is consistency: taking your injections exactly as prescribed, following your nutrition and activity plan, and staying in touch with your care team. Your clinician will adjust your dose over time based on how you’re responding and any side effects you experience.

As a general medical guideline, a safe rate of weight loss is often around 1–2 pounds per week (about 4–8 pounds per month), though your individual pace may be slower or faster depending on your starting point, health conditions, and goals. With Zepbound®, Fittlly’s focus is on steady, sustainable progress, not extreme or rushed weight loss.

Zepbound® (tirzepatide) injections are available to many patients across the United States, but access can vary by state due to local telehealth and prescribing regulations. During your online eligibility check, we’ll ask for your location and clearly show whether Fittlly can prescribe and ship Zepbound® to your state.

If Zepbound® is not available where you live, your clinician may discuss alternative treatment options that are safe and appropriate for your situation.

Eligibility for Zepbound® (tirzepatide) is always determined by a licensed clinician after a full review of your medical history, current medications, and goals. Zepbound® is not suitable for everyone, and it is only prescribed when it is medically appropriate and safe.

In general, patients considered for Zepbound® typically:
• are 18 years of age or older
• have a BMI of 27 or higher
• are not pregnant or breastfeeding
• do not have certain medical conditions, such as:
  o a history of certain thyroid cancers or serious thyroid disease
  o gastroparesis (significantly delayed stomach emptying)
  o pancreatic cancer or pancreatitis
  o MEN2 (multiple endocrine neoplasia type 2)
  o some forms of inflammatory bowel disease

This is not a complete list of eligibility criteria. As part of the Fittlly process, you’ll complete an online health screening with our telehealth clinicians. Based on this evaluation, they will decide whether Zepbound® is an appropriate and safe option for you, or whether another treatment approach would better fit your needs.

There isn’t a strict “Zepbound® diet,” but what and how you eat will strongly influence how you feel on treatment and how effective it is. Your doctor or dietitian may give you personalized recommendations, and it’s important to follow their advice.

In general, a balanced way of eating and regular movement will support weight loss, help manage side effects, and make Zepbound® work better for you. Many patients feel better when they:
• Limit heavy, greasy, fried, and high-sugar foods, which can worsen nausea or digestive discomfort
• Reduce alcohol intake, as it can affect blood sugar and digestion
• Stay well hydrated, by drinking enough water throughout the day

Your Fittlly care team can help you choose an eating pattern that fits your lifestyle, health, and goals while working alongside your Zepbound® treatment.

Like all prescription medicines, Zepbound® (tirzepatide) can cause side effects. Many are mild to moderate and improve as your body adjusts to treatment, especially when the dose is increased gradually.

Common side effects can include:
• nausea or vomiting
• diarrhea or constipation
• abdominal pain or discomfort
• bloating, burping, or indigestion
• decreased appetite
• headache, fatigue, or dizziness

Not everyone will experience these symptoms, and for many patients they become less frequent over time.

Less common but more serious side effects may include:
• severe or persistent abdominal pain (which could signal pancreatitis)
• gallbladder issues, such as gallstones or inflammation
• signs of dehydration (very little urine, feeling faint, very dry mouth)
• changes in vision, especially in people with diabetes
• possible thyroid-related issues, including a lump in the neck, hoarseness, or difficulty swallowing
• allergic reactions, such as rash, swelling, or trouble breathing

If you notice severe, sudden, or worrying symptoms, seek medical help right away and contact your healthcare provider.

Do not change your dose or stop Zepbound® on your own. If you’re concerned about side effects, speak with your Fittlly clinician or your primary care provider. They can review your symptoms, adjust your treatment if needed, and help you manage side effects safely. Always refer to the medication guide and official prescribing information for the full list of potential risks and side effects.

If you forget to take a scheduled Zepbound® injection, you can usually take the missed dose as soon as you remember as long as no more than 4 days have passed since the day you were supposed to inject.

If more than 4 days have gone by, skip the missed dose and wait until your next scheduled injection. Then continue with your regular once-weekly schedule. Do not inject two doses close together or take a “double dose” to make up for the one you missed.

If you’ve missed more than one dose, or you’re unsure what to do, contact your Fittlly clinician or your primary healthcare provider. They can advise you on the safest way to restart, delay, or adjust your dosing schedule.

To keep your Zepbound® (tirzepatide) treatment safe and effective, it’s important to store and dispose of your pens, needles, and medication correctly.

Storage:
• Keep all medicine pens, vials, syringes, and needles out of reach of children and pets.
• Store your medication away from direct light and heat, following the instructions on the package and pharmacy label.
• Refrigerate unused Zepbound® between 36°F and 46°F (2°C–8°C), and avoid placing it directly next to the cooling element.
• Do not freeze Zepbound®. If the medication has been frozen at any point, do not use it—dispose of it safely.
• Always check the expiration date or beyond-use date and do not use medication that is out of date.

Disposal:
• Used pens and needles should go into an approved sharps container or a sturdy, puncture-resistant container, according to your local regulations.
• Do not throw loose needles, syringes, or pens directly into household trash, and do not flush medications down the toilet or pour them into the sink unless you are specifically instructed to do so.
• Whenever possible, use a medicine take-back program or follow local guidelines for disposing of unused or expired medication. Your pharmacist or local waste authority can help you find safe disposal options in your area.

If you are unsure how to store or dispose of your Zepbound® safely, ask your pharmacist or clinician—they can give you guidance tailored to your prescription and location.